The Luger lab started in January of
1999 with two postdocs, Ernst Schönbrunn
and Robert Suto and one graduate
student, Cindy White. In addition to
establishing a biochemistry lab, our first task was to purchase and
implement diffraction equipment and to equip a molecular graphics
lab. X-ray facilities were operational in May of 1999, and we
first structure in fall of the same year.
Our program received a kick-start with a grant from the
Searle Scholars program, and we were awarded our first
NIH grant in February of 2000. The lab grew rapidly in size to
its ‘steady state’ size of about 10 researchers and 2-4
undergraduates. Our second NIH grant followed in 2002; this grant is now in its second cycle.
In 2002, Drs. Nyborg, Laybourn, Hansen, and Luger were
awarded a grant from the
W. M. Keck foundation to equip and staff protein purification
facilities, and to equip the second port of our existing X-ray
generator for data collection.
In 2003, Karolin Luger was named a
Monfort Professor, and in 2005 was selected as an
Investigator for the Howard Hughes Medical Institute. In 2007, Luger was named one of thirteen University Distinguished Professors. She is affiliated with the University of Colorado School of Medicine, Department of Biochemistry and Molecular Genetics.
In 2010, Drs. Luger, Nyborg and Stargell were awarded a program project grant to study structural and functional links between histone chaperones and histone acetylation.