“I am a graduate student in the Luger lab investigating the structure of nucleosomes in giant DNA viruses. When not in the lab, I enjoy hiking, teaching color guard and the company of any dog.”
I’m a fifth year graduate student with a focus on the biophysics and biochemistry of protein-protein and protein-nucleic acid complexes. My approach emphasizes analytical ultracentrifugation (AUC) and x-ray crystallography, complemented by various biochemistry methods.
I am studying the interactions of Poly ADP-Ribose Polymerase 1 (PARP1) and Histone PARylation Factor 1 (HPF1) by probing the kinetics and thermodynamics of this interaction. When not in lab, Genny enjoys visiting new breweries, listening to podcasts and volunteering with local politics.
I’m a graduate student in the Luger Lab that uses techniques such as FRET, AFM, and Cryo-EM to better understand how proteins interact with nucleosomes. When I’m not in the lab, I enjoy skiing, running, and playing soccer.
In recent years, it was discovered that archaeal genomes encode homologs of eukaryotic histones, but exactly how these predicted histones function and whether they are the precursors to eukaryotic histones remains to be seen. Through a combination of computational genomics, structural biology, and biophysics I hope to address these questions and uncover fundamental aspects of archaeal biology. In addition to graduate school, I’m an avid runner, skier, pie baker, and fan of the color orange.