Karolin Luger, Ph.D. PI, and Chief Lab Wrangler

Training: Ph.D. in Biochemistry and Biophysics from the University of Basel in Switzerland; postdoctoral fellow and research assistant professor at the Swiss Federal Institute of Technology in Zuerich.
Main research interest: Structural biology of chromatin

Shanna Roemen, Admin Coordinator, Luger Lab

Shanna joined the Luger Lab in April, 2018 as Admin Coordinator. Shanna oversees all the administrative functions, media, travel and financials.

Hobbies: Beach Bum, Motocross Mom and Gardening

Pamela Dyer, Lab Manager II

Luger Lab Manager since May 2001
BS Science, Oregon State University
Horticulture (fruit and vegetable production and genetics)
Specialist in Molecular Biology certificate 2000

Jack of all trades in the lab: Reagent prep, Equipment maintenance, Lab Ordering, Research projects, Resource Management, Organization, Therapist/Life coach, Lab Mom.

Hobbies: Gardening, Tennis, Hiking, Camping


Alison White, Professional Research Assistant

Alison is a Colorado native who completed dual Bachelors of Science in zoology and biology  from CSU in 2005. She went on to join Karolin Lugers lab to complete a MS in Cell and Molecular Biology at CSU in 2007. She continued in Karolin’s lab working on several different main projects over the years, including linker histone H1 and exploring zinc finger proteins binding the nucleome. She has had several side projects including work with RTT109 acetylation, VPS/NAP1 tail swaps, Archaea histones, making DNA for lab consumption and maintaining several pieces of equipment including the Atomic Force Microscope. When not hard at work in the lab, Alison is passionate about volunteering, especially for veterans and animal rescue organizations. She also enjoys nature photography, knitting, and gardening.



  • A quantitative investigation of linker histone interactions with nucleosomes and chromatin.
    White AE, Hieb AR, Luger K. Sci Rep. 2016 Jan 11;6:19122.
    PMID: 26750377
  • Fluorescence strategies for high-throughput quantification of protein interactions.
    Hieb AR, D’Arcy S, Kramer MA, White AE, Luger K. Nucleic Acids Res. 2012 Mar;40(5):e33.
    PMID: 22121211
  • Structure of histone-based chromatin in Archaea Mattiroli F, Bhattacharyya S, Dyer PN, White AE, Sandman K, Burkhart BW, Byrne KR, Lee T, Ahn NG, Santangelo TJ, Reeve JN, Luger K. Science. 2017 Aug 11;357(6351):609-612. doi: 10.1126/science.aaj1849. PMID: 28798133

Sofia Rae, Professional Research Assistant

Sofia is currently working on human PARP1 and PARP2 expression and purification. In spare time, makes stocks of DNA for the lab, updates lab’s plasmid library, and is in the process of cloning 12 copies of a strand of DNA into a plasmid vector. Graduated with a bachelors in Biochemistry from the University of Colorado, Boulder in 2018, and began working for Luger Lab full time that summer

Emma Denning, Professional Research Assistant

Graduated with a bachelors in Molecular and Cellular Developmental Biology from the University of Colorado, Boulder in 2019. Originally from Georgia, she is continuing the human PARP1 and PARP2 expression and purification project along with maintaining and updating the lab’s plasmid library